PISCATAWAY, NJ—Despite the legalization of cannabis sales in Canada and many U.S. states, an illegal market still exists. A new study in the Journal of Studies on Alcohol and Drugs suggests that higher prices and inconvenience associated with legal sources may be barriers that encourage consumers to seek out illegal providers instead. Credit: Katherine Hitthttps://www.flickr.com/photos/[email protected]/4420604477
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pDNA/dbDNA design, cloning and manufacture All sequences for the standard DNA lentiviral constructs (eGFP transgene, GagPol, Rev and VSG) were obtained from Addgene (www.addgene.org) choosing from widely used lentiviral third-generation production systems. Those sequences were synthesised de novo and cloned into Touchlight’s proTLx backbone at Genewiz (www.genewiz.com) or Genscript (www.genscript.com). The resulting plasmids (pDNA) were
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Within a few years, synthetic biology has evolved from being a new player in the molecular biology and biotech arena to being a front-row contender with multiple industrial advances and large amounts of investor money.  There have been a number of definitions of synthetic biology, also known as synbio. Generally, it involves redesigning genetic systems
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Rice University synthetic biologists and bioengineers are preparing to interrogate some single-celled survivalists to find out how they deal with stress. Bacillus subtilis is a common soil bacteria with an outsized reputation for handling stress. It’s the model organism biologists use to study spore formation, a life-or-death gamble that requires precision timing under the worst
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It is the first gene therapy to be directly administered into the brain to treat aromatic L-amino acid decarboxylase (AADC) deficiency Both the European Medicines Agency (EMA) and the Committee for Medicinal Products for Human Use (CHMP) has recommended PTC Therapeutic’s gene therapy, Upstaza (eladocagene exuparvovec), for patients 18 months and older with aromatic L-amino
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Breakthrough COVID-19 cases resulting in infections, hospitalizations and deaths are significantly more likely in cancer and Alzheimer’s patients, according to two new studies from researchers at the Case Western Reserve University School of Medicine. People within these diseases are often more susceptible to infection in general, the researchers explained, and are among the population’s most
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Telehealth company Amwell has marked Mental Health Awareness month with the launch of a digital tool that will deliver cognitive behavioural health interventions across a spectrum of mental illness. The suite – which combines virtual therapy and psychiatry, optional coaching, and digital mental health programmes tailored to the patient’s needs – has been developed in
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Following our recent acquisition by Inova, our team is expanding! We’re very excited to welcome three new hires to join our international team: Jim, former Editor at DairyReporter, is joining us as Editor-in-Chief. As a music composer, photographer, and podcaster, he is looking to bring in loads of creative energy and explore fun ways to
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Gifford is supporting the launch with a philanthropic donation of £14.7m A new multi-million-pound pandemic science hub is being created, to develop treatments for lung infections such as COVID-19 and prepare the UK for similar future pandemics. The research programme was announced at the University of Edinburgh, with support from a significant donation from Baillie
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A recent study published in the journal Viruses reported that antibody titers against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) could serve as a marker for the severity of coronavirus disease 2019 (COVID-19). COVID-19 manifests as a mild asymptomatic disease to acute respiratory disease syndrome (ARDS). The condition is often biphasic, with ARDS developing some days
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How effective environmental measures in agriculture are for biodiversity and wild bee populations depends on various factors and your perspective. This is shown by agroecologists from the University of Göttingen, Germany and the Centre for Ecological Research in Vácrátót, Hungary. The research team found that when assessing the effectiveness of different measures, whether in the
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The results of LC–MS analysis As shown in Fig. 1, in the present study, under optimal chromatographic and MS conditions14,15, 3 compounds were identified by comparing the retention times and matching the empirical molecular formulas with those of known saponins; six phenolic compounds, seven fatty acid compounds, three nucleotide compounds, five quinone compounds, six carbohydrate compounds,
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Scientists demonstrated that AZD1236 halts oedema while reducing spinal cord breakdown at the site of the injury Research from the University of Birmingham has shown that an existing drug may reduce damage following spinal cord injury by blocking the inflammatory response in the spinal cord. The scientists demonstrated that AZD1236, a drug developed by AstraZeneca,
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The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health awarded the UNC Gillings School of Global Public Health a $65 million grant establishing an Antiviral Drug Discovery Center to develop oral antivirals that can combat pandemic-level viruses like COVID-19. The center builds upon and is tightly affiliated with UNC’s
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