Month: February 2021

Rare diseases affect a fraction of the population – 450 million+ people globally. However, its effects can be equally severe and life-threatening as other prevalent diseases. For Rare Disease Day, Tarun Kumar Bansal discusses why we need to expedite innovation in the rare disease domain. Every time a patient with a rare condition walks into
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Korea Brain Research Institute (KBRI, President Suh Pann-ghill) announced that the research team led by Dr. Jae-Yeol Joo discovered new cryptic splice variants and SNVs in PLCg1 gene of AD-specific models for the first time using Splice-AI. This research outcome was published in PNAS, a world-renowned academic journal. * (Title) Prediction of Alzheimer’s Disease-Specific phospholipase
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Natural killer cells are becoming a hot topic in the booming cancer cell therapy scene, with the field’s latest big deal being a €640M licensing agreement between the French biotech Cellectis and US company Cytovia.  T-cell immunotherapies like CAR T-cell therapy have revolutionized cancer treatment in recent times. However, they have a significant disadvantage. The
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Abundant expression of Postn in neonatal tendons The basic building blocks of tendons are type-I ECM collagen fibers, which are composed of highly parallel-aligned fibrils deposited by tendon cells. The number of proliferating cells was reported to be greater in the tendon ECM niche from 3-day-old mice than from 6-week-old mice2. Compared to the 6–8-week-old
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Insilico Medicine has demonstrated a breakthrough in Artificial Intelligence (“AI”) and drug discovery — linking together generative chemistry and biology for the first time — to discover a novel preclinical candidate addressing idiopathic pulmonary fibrosis (“IPF”) and be validated with multiple human cell and animal model experiments. Often found implicated in a wide range of
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The global pandemic promised a windfall for forward-thinking companies making products to help combat the spread of the coronavirus. Count the Stevanto Group, one of the world’s foremost makers of glass vials, among them. Since the onset of the pandemic, business has been booming at the 72-year-old Italian company, so much so that Stevanto is
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A University of Texas at Arlington researcher has received an Office of Naval Research (ONR) grant to examine the mechanics of how blast-like events cause damage to the brain. Ashfaq Adnan, professor of mechanical and aerospace engineering, has received a three-year, $944,845 grant to study the potential link between blast-like trauma and cellular and tissue
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A University of Texas at Arlington researcher has received an Office of Naval Research (ONR) grant to examine the mechanics of how blast-like events cause damage to the brain. Ashfaq Adnan, professor of mechanical and aerospace engineering, has received a three-year, $944,845 grant to study the potential link between blast-like trauma and cellular and tissue
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Field attributes of indigenous farmer’s varieties collected from sub-Himalayan Terai region A total of ninety-nine genotypes collected from different region of sub-Himalayan Terai region were subjected to purity breeding for at least five years and the pure lines were deposited to the Uttar Banga Krishi Viswavidyalaya (UBKV) rice repository. The performance of the genotypes for morphological and
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A month after Johnson & Johnson’s COVID-19 vaccine posted positive data in a phase 3 study, the shot is almost ready for prime time. Late Friday, a key panel unanimously endorsed the vaccine for emergency use and sent it to the agency for an official decision. An FDA authorization for the one-dose vaccine would provide a quick lift
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Wayra and GE Healthcare have launched an accelerator programme across the Europe, the Middle East and Africa (EMEA) region to support digital health start-ups to develop AI applications for healthcare. The Edison Accelerator will initially support six start-ups in its first cohort, which will focus on applying AI to medical imaging, operational AI in oncology
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Researchers at the Lady Davis Institute (LDI) at the Jewish General Hospital have discovered that increased levels of the protein OAS1 are associated with reduced mortality and less severe disease requiring ventilation among patients with COVID-19. Using drugs that boost OAS1 levels could be explored to try to improve these outcomes. The findings are published
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