Month: September 2021

Quantification of ratio of full cell membrane coating The acquisition of cell membrane material used for coating usually involves two steps: extracting cell membranes from harvested cells and extrusion through porous membranes to create cell membrane-derived vesicles6. We hypothesized that this resulting mixture of cell membrane fragments and vesicles (Supplementary Fig. 1) fusing with NPs by
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Grégoire Courtine doesn’t hesitate to use the word “revolutionary” when describing the emerging field of optogenetics – a technology that uses pulses of light to control individual neural activity – and what it could mean for neuroscience. Courtine, director of the NeuroRestore research center (with neurosurgeon Jocelyne Bloch), is currently developing an optogenetic implant together
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Argenx’s dive into rare disease myasthenia gravis (MG) swept three categories in the third annual Fierce Pharma Marketing Awards, which were held Wednesday night. Chosen as the best online film or video, best medical conference or event marketing for its premiere event and best consumer website, the trifecta came as a surprise to the winning pharma.
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People with advanced or metastatic urothelial cancer will soon have access to a new treatment option following a NICE recommendation. Final draft guidance from NICE is set to arrive on Friday 1 October for the intravenous injection. The life-extending drug, atezolizumab, is recommended for people unsuitable for platinum containing chemotherapy, and whose tumour expresses PD-L1
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Plaque and phage morphology of DRL-P1 Isolated phage was initially screened against P. aeruginosa through spot tests. A clear zone over a bacterial lawn was observed due to the lytic activity of the phage (Fig. 1a). This phage was named ‘DRL-P1’. On double-layer agar (DLA) plates, DRL-P1 produced small but clear plaques of approximately 2 ± 0.23 mm diameter
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A drug candidate discovered and developed decades ago in the laboratory of UC Davis distinguished professor Bruce Hammock may help control the body’s raging and often deadly inflammatory response to chemotherapy treatments, especially for pancreatic and liver cancer patients. The research team, based in the laboratories of Dipak Panigrahy at Harvard Medical School and Hammock,
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The road to certification for Biocon’s insulin facility in Malaysia was long, winding and full of potholes. Now comes a detour. The FDA has slapped the factory with Form 483, citing six observations that need to be addressed, the company said. The site makes the high-profile interchangeable insulin Semglee, but Biocon doesn’t expect the latest inspection
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Since the first reported coronavirus disease 2019 (COVID-19) case in December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome has continued to mutate and evolve. Some mutations in the SARS-CoV-2 genome might influence the development of effective intervention strategies. Study: Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of
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ALBUQUERQUE, N.M. — Somewhere among the glitter of the night sky is a small satellite powered by innovative, next-generation solar cell technology developed at Sandia National Laboratories. ALBUQUERQUE, N.M. — Somewhere among the glitter of the night sky is a small satellite powered by innovative, next-generation solar cell technology developed at Sandia National Laboratories. mPower
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This study demonstrates a simplified lentiviral vector optimization that is cost and time effective and produces highly efficient transduction in CCs in transfection method, the relative ratio of transfer, packaging and envelope plasmids, viral titering and purification, concentration method, as well as selection method of cells carrying the transgene, as illustrated in Fig. 5. HEK293T cells
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Hamilton Company and Rhinostics, an early-stage Harvard University spin-out company, are combining their respective strengths to improve the speed and quality of nasal and nasopharyngeal sample workflows from collection to processing while also reducing the need for active labor involvement. This sample type is widely used to detect antibodies and antigens in relation to the
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