This thought leadership series has been paid and developed by Kite, a Gilead Company. This Blood Cancer Awareness Month, Blood Cancer UK’s Kate Keightley explains the need for better awareness and understanding of this common, but less-understood disease. Blood cancer is the fifth most common cancer in the UK and the third most deadly, killing
Month: September 2021
Quantification of ratio of full cell membrane coating The acquisition of cell membrane material used for coating usually involves two steps: extracting cell membranes from harvested cells and extrusion through porous membranes to create cell membrane-derived vesicles6. We hypothesized that this resulting mixture of cell membrane fragments and vesicles (Supplementary Fig. 1) fusing with NPs by
Grégoire Courtine doesn’t hesitate to use the word “revolutionary” when describing the emerging field of optogenetics – a technology that uses pulses of light to control individual neural activity – and what it could mean for neuroscience. Courtine, director of the NeuroRestore research center (with neurosurgeon Jocelyne Bloch), is currently developing an optogenetic implant together
Argenx’s dive into rare disease myasthenia gravis (MG) swept three categories in the third annual Fierce Pharma Marketing Awards, which were held Wednesday night. Chosen as the best online film or video, best medical conference or event marketing for its premiere event and best consumer website, the trifecta came as a surprise to the winning pharma.
People with advanced or metastatic urothelial cancer will soon have access to a new treatment option following a NICE recommendation. Final draft guidance from NICE is set to arrive on Friday 1 October for the intravenous injection. The life-extending drug, atezolizumab, is recommended for people unsuitable for platinum containing chemotherapy, and whose tumour expresses PD-L1
Many people are confronted with chronic pain that can last for months or even years. How to best treat chronic pain? First, pain must be categorized for the right treatment to be prescribed. However, is that it is very challenging for patients to define their pain, its intensity or even its location using questionnaires. To
Mast cell precursor cells do not just cause an increase in mature mast cells during inflammation, they also play an active role in diseases like asthma. This finding is in a new study by immunology researchers published in the Journal of Allergy and Clinical Immunology. The study also emphasises that precursor cells in general can
Across the first phase of the pandemic, AstraZeneca went from being a good example of how pharma can step up in times of need to a warning that no good deed goes unpunished. Now, AstraZeneca has a shot at putting its vaccine woes behind it by carving out a space for a product that may
A research project between Bayer and digital health company Huma will use artificial intelligence to detect lung cancer in CT scans – and determine which type a patient has, in order to direct treatment. AI is already being applied by a number of groups, with some studies indicating it can even be more effective than
Plaque and phage morphology of DRL-P1 Isolated phage was initially screened against P. aeruginosa through spot tests. A clear zone over a bacterial lawn was observed due to the lytic activity of the phage (Fig. 1a). This phage was named ‘DRL-P1’. On double-layer agar (DLA) plates, DRL-P1 produced small but clear plaques of approximately 2 ± 0.23 mm diameter
A drug candidate discovered and developed decades ago in the laboratory of UC Davis distinguished professor Bruce Hammock may help control the body’s raging and often deadly inflammatory response to chemotherapy treatments, especially for pancreatic and liver cancer patients. The research team, based in the laboratories of Dipak Panigrahy at Harvard Medical School and Hammock,
The road to certification for Biocon’s insulin facility in Malaysia was long, winding and full of potholes. Now comes a detour. The FDA has slapped the factory with Form 483, citing six observations that need to be addressed, the company said. The site makes the high-profile interchangeable insulin Semglee, but Biocon doesn’t expect the latest inspection
According to a report from the Association of the British Pharmaceutical Industry (ABPI), the UK is taking longer to recover from the COVID-19 pandemic than its European peers. The pandemic has significantly impacted the type of clinical trials conducted, and how these are designed and delivered. However, it has also highlighted the value of clinical
Since the first reported coronavirus disease 2019 (COVID-19) case in December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome has continued to mutate and evolve. Some mutations in the SARS-CoV-2 genome might influence the development of effective intervention strategies. Study: Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of
ALBUQUERQUE, N.M. — Somewhere among the glitter of the night sky is a small satellite powered by innovative, next-generation solar cell technology developed at Sandia National Laboratories. ALBUQUERQUE, N.M. — Somewhere among the glitter of the night sky is a small satellite powered by innovative, next-generation solar cell technology developed at Sandia National Laboratories. mPower
Amicus has endured a tough few years of pipeline flops and a roller coaster stock ride, but now it’s riding the special purpose acquisition company wave, spinning off its gene therapy unit in a $600 million deal. The pact sees Amicus’ gene therapy business bought out by ARYA Sciences Acquisition Corp IV, a SPAC sponsored
Artificial intelligence (AI) has become a part of everyday modern life and continues to generate excitement. In this article, we will take a look at how biotechs are advancing into AI-facilitated early drug design, its real-world outcomes so far, and whether it is living up to its potential in the life science industry. AI enables
Prospects for Valneva’s COVID-19 vaccine are up in the air, but another candidate partnered with Pfizer looks increasingly like it could fill the void of an effective shot for Lyme disease. New phase 2 data with their VLA15 vaccine shows that antibody responses from an initial three-dose regimen are initially high, although they start to
This study demonstrates a simplified lentiviral vector optimization that is cost and time effective and produces highly efficient transduction in CCs in transfection method, the relative ratio of transfer, packaging and envelope plasmids, viral titering and purification, concentration method, as well as selection method of cells carrying the transgene, as illustrated in Fig. 5. HEK293T cells
Hamilton Company and Rhinostics, an early-stage Harvard University spin-out company, are combining their respective strengths to improve the speed and quality of nasal and nasopharyngeal sample workflows from collection to processing while also reducing the need for active labor involvement. This sample type is widely used to detect antibodies and antigens in relation to the
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