Month: January 2022

Mouse breeding All animal experimental protocols and relevant ethical regulations were followed, and the study was approved by the Animal Care and Use Committee of The Johns Hopkins University, Baltimore, MD, USA (Protocol number: MO21M276). The Advillin-Cre (Avil-Cre) mouse strain was kindly provided by Xingzhong Dong (Department of Neuroscience, The Johns Hopkins University, Baltimore, MD,
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Researchers from universities across the UK, led by the University of Bristol, have been awarded £4.9 million from the Biotechnology and Biological Sciences Research Council (BBSRC), the UK’s largest bioscience funder, to investigate how electrons and energy flow through biological molecules by building artificial protein-based wires and circuits. This promises new ‘green’ catalysts, and biomolecular
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Worry not, Wegovy fans: There’s reason to believe supply of Novo Nordisk’s obesity med could resume as planned by the middle of the year. That’s according to Jefferies analysts’ chat with a manufacturing expert, who weighed in on the FDA write-up at a Catalent facility behind the production dilemma. As Novo Nordisk suggested, Catalent could
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MHRA awards a positive scientific opinion for voxelotor–a once-daily tablet for the treatment of haemolytic anaemia Global Blood Therapeutics (GBT) has announced that the Medicines and Healthcare products Regulatory Agency (MHRA) has awarded a positive scientific opinion–under the Early Access to Medicines Scheme (EAMS)–for voxelotor. The treatment is an oral once-daily tablet under review by
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Tokyo, Japan – Researchers from Tokyo Metropolitan University have succeeded in using nanowires of a transition-metal chalcogenide to make atomically thin “nanoribbons”. Bundles of nanowires were exposed to a gas of chalcogen atoms and heat which helped merge the threads into narrow strips. Nanoribbons are highly sought after for sophisticated electronic devices; given the scalability of
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Our research complies with all relevant ethical regulations as detailed in the below sections. Tissue collection and non-lactating cell isolation Non-lactating human breast tissue was donated by participants who provided informed consent who were undergoing elective aesthetic reduction mammoplasty at the Nymphenburg Clinic for Plastic and Aesthetic Surgery in accordance with the regulations of the
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Discovery scientists using traditional tech often need to make go-no-go decisions on sub-optimal data, says Charles River Laboratories, which has expanded its deal with SAMDI Tech to try and give sponsors more information about candidate compounds. CRL announced the move this week, explaining it has become the only contract research organization (CRO)—other than SAMDI—that can
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The first doses of an experimental HIV vaccine have been delivered in a phase 1 clinical trial. International AIDS Vaccine Initiative (IAVI), a non-profit scientific research organisation – alongside biotechnology company Moderna and the Bill & Melinda Gates Foundation – aims to build on the results seen in a proof-of-concept trial for the associated antigens.
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If you are considering a career in bioengineering, it is important that you understand what the field entails and whether it is right for you. Bioengineering is a broad field that covers many aspects of science and engineering, from medical device design to plant biology. It is a challenging and rewarding field, but it is
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The experiment conducted herein was approved by the Institutional Animal Care and Use Committee of the University of Tennessee (protocol no. 2655-0219). All experimental procedures were performed in accordance with the animal ethics approval and regulations. The study was carried out in compliance with the ARRIVE guidelines. Experimental design A total of thirty-two (1- to
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Kaleido Biosciences confirmed it has shrunk its workforce. The Flagship Pioneering-incubated biotech also halted work on a planned phase 2 trial in chronic obstructive pulmonary disease and terminated its agreement with the COPD Foundation, announced just five months ago. CEO Dan Menichella confirmed the layoffs in an emailed statement to Fierce Biotech. Stoppage of the phase 2
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