Biotech

Thought LeadersHenry FingerhutSenior Policy Analyst for Science & InnovationTony Blair Institute for Global Change In this interview, News-Medical speaks to Henry Fingerhut, Senior Policy Analyst for Science & Innovation at the Tony Blair Institute for Global Change, about genomic surveillance and its associated opportunities and challenges. In collaboration with Professor Derrick Crook of Oxford’s Nuffield
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Researchers announced early tests of a new potato processing technique designed to make our bodies digest potato starch more slowly. Laboratory demonstrations show that the approach blocks certain digestive enzymes from reaching the potato starch as quickly, leading to a more controlled release of dietary glucose. There is a perception that potato foods are unhealthy
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A new study published in Nature today has identified a potential Achilles heel in the protective layers surrounding Gram-negative bacteria that could aid in the development of next-generation antibiotics. The study, carried out jointly by Professor Waldemar Vollmer and Dr Federico Corona at Newcastle University, alongside Professor Colin Kleanthous and Dr Gideon Mamou in the
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In a recent study published in the journal Nature Biotechnology, an international team of researchers developed and evaluated quantitative polymerase chain reaction (qPCR)-based assays to quantify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific functional T cell immunity. Study: Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR. Image Credit: Instituto de Salud Carlos III /
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In a recent study posted to the medRxiv* pre-print server, scientists at nference Labs investigated the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron’s unique spike (S) gene insertion ins214EPE. It is an in-frame insertion of nine nucleotides between positions 22204 and 22207, constituting a ribonucleic acid (RNA)
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The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including Whitehead Institute, and was finally completed in 2003. Now, over two decades later, Whitehead Institute Member Jonathan Weissman and colleagues have gone beyond the sequence to present the
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Analyzing brain stem cells of patients with autism spectrum disorder (ASD), Rutgers scientists have found evidence of irregularities in very early brain development that may contribute to the neuropsychiatric disorder. The findings support a concept scientists have long suspected: ASD arises early in fetal development during the period when brain stem cells divide to form
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A new study presents a novel approach to drug repurposing that incorporates two-stage prediction and machine learning. The study is published in the peer-reviewed OMICS: A Journal of Integrative Biology. Drug repurposing is a method of developing new therapeutic use(s) for existing drugs, for which safety and pharmacokinetics have already been demonstrated in humans. This
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Single-cell RNA-sequencing (scRNA-seq) shows which genes are turned on in a cell and what their level of transcription is. This allows in-depth assessment of the biology of individual cells, and detection of changes that may indicate disease. scRNA-seq is becoming widely used across disciplines including developmental biology, neurology, oncology, immunology, cardiovascular research and infectious diseases. It is critical for
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Researchers at Tulane University School of Medicine have developed a new highly sensitive blood test for tuberculosis (TB) that screens for DNA fragments of the Mycobacterium tuberculosis bacteria that causes the deadly disease. The test could give doctors a new tool to both quickly identify TB and then gauge whether drug treatments are effective by
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In a recent study posted to the Research Square* preprint server, researchers characterized infections caused by the monkeypox virus (MPXV). Study: Multi-country outbreak of monkeypox virus: phylogenomic characterization and signs of microevolution. Image Credit: Kateryna Kon/Shutterstock Monkeypox is caused by MPXV belonging to the Orthopoxvirus genus, which also comprises the variola virus, which causes smallpox.
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In a recent study published in the journal Nature Biotechnology, researchers introduced deep visual proteomics (DVP), an amalgamation of artificial intelligence (AI) for image analysis and mass spectrometry (MS) for proteomic profiling of biological samples. Existing proteomic analysis techniques are limited in their ability to image tissues at single-cell resolution and usually target a pre-defined
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Rice University synthetic biologists and bioengineers are preparing to interrogate some single-celled survivalists to find out how they deal with stress. Bacillus subtilis is a common soil bacteria with an outsized reputation for handling stress. It’s the model organism biologists use to study spore formation, a life-or-death gamble that requires precision timing under the worst
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