Scientists have worked at an unprecedented speed to develop vaccines to fight against the ongoing coronavirus disease 2019 (COVID-19) pandemic. This pandemic has been caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus belonging to the family Coronaviridae. Study: Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents. Image Credit: NIAID Background It
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Generation of knock-down resistance alleles of the voltage-gated sodium ion channel in Drosophila Pyrethroids and DDT bind to the voltage-gated sodium channels (VGSCs) triggering abnormal channel activity but are unable to bind or disrupt function of Knockdown-resistant (Kdr) mutant channels. The most widespread kdr alleles in Anophelines include L1014F, whereas I1011M/V are prevalent in Aedes
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We’re off for another day of the J.P. Morgan Healthcare Conference. We saw a clamor of research collaboration announcements that defined the first two days of the conference. Now, those announcements have slowed, but there’s plenty of action to come as companies make their pitches to their peers, investors and industry watchers.    And we’re
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Immune cell monitoring is imperative for almost any clinical study. The problem: Current procedures require viable cells, a demand often torpedoed by sample logistics. Eva Raschke, Director of Scientific Affairs at Precision for Medicine What do cancer, autoimmune diseases, and Covid-19 have in common? Hint: Think of immune cells. In immuno-oncology, therapeutic approaches provoke a
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insights from industryDr. Zhang Lin LinTechnical SpecialistSino Biological Europe In this interview, News-Medical talks to Dr. Zhang Linlin, Technical Specialist at Sino Biological Europe, about their recombinant antibody services and more that they can provide within Europe. Can you explain what services Sino Biological provides? Sino Biological is dedicated to providing the scientific community with
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Order up. Shortly after topping off supplies of COVID-19 drugs from Pfizer and GlaxoSmithKline, the U.S. has asked for a second helping of AstraZeneca’s antibody combo. The government has purchased an additional 500,000 doses of AZ’s long-acting antibody cocktail Evusheld, or tixagevimab plus cilgavimab. That comes on top of 700,000 doses the U.S. already ordered,
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When male workers believe their gender status is threatened, they are more likely than their female counterparts to engage in deviant behavior such as lying, cheating or stealing in the workplace, new research suggests. They also become less helpful to co-workers and less willing to collaborate on organizational initiatives, said Oregon State University’s Keith Leavitt,
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Plasmid construction Sequence of the affinity clamp (PDZ-fibronectin fusion protein) was extracted from the PDB file 3CH8. Sequences of the anti-HSA scFv and Fab antibody fragments were derived from the PDB file 5FUO or from the US_2014_0186365 patent (sequence 4D2). Sequences of the anti-IL-6 scFv, anti-IL-6 Fab, anti-IFNα-1b scFv, and anti-IFNα-2a Fab were derived from the following
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Sana Biotechnology will dish out up to $204 million in biobucks to gain nonexclusive access to a BCMA CAR construct from IASO Biotherapeutics and partner Innovent Biologics.  The construct is part of IASO and Innovent’s autologous BCMA-directed CAR-T cell therapy, CT103A, that is in a phase 1/2 study in patients with relapsed and/or refractory multiple
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Ahead of its state-of-the-company address at the J.P. Morgan Healthcare Conference, AbbVie took the unusual step of reconfirming its guidance for its blockbusters-in-waiting Rinvoq and Skyrizi, saying it expects the duo’s sales to reach a combined $15 billion in 2025. Why update an estimate that hasn’t changed? While AbbVie expects the two to produce the
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The partnership between Oxford University and SEEQC promises to accelerate the use of quantum computing within pharmaceutical research in order to reduce the development time required for drug production worldwide. Oxford University has joined a consortium led by the digital quantum computing company, SEEQC, to build and deliver a full-stack quantum computer for pharmaceutical drug
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Researchers at Penn Medicine have discovered a new, more effective method of preventing the body’s own proteins from treating nanomedicines like foreign invaders, by covering the nanoparticles with a coating to suppress the immune response that dampens the therapy’s effectiveness. When injected into the bloodstream, unmodified nanoparticles are swarmed by elements of the immune system
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As the COVID-19 pandemic continues to impact the healthcare landscape, and the digital transformation of the life sciences industry gathers pace, what can we expect to see in 2022? In this webinar, senior members from Healthware Group discuss the key trends and developments set to shape the industry and present their predictions for the year
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